John Wayne Casserole
This hearty John Wayne Casserole is a Tex-Mex delight that brings the spirit of the Wild West to your dinner table.
Packed with layers of savory ground beef, zesty vegetables, and gooey cheese, it’s a crowd-pleasing dish that’s both comforting and flavorful.

Named after the iconic actor, this casserole embodies the rugged, satisfying essence of cowboy cuisine with a modern twist.
Ingredients
- 2 cups biscuit baking mix
- 1 cup water
- 1 pound ground beef
- 1 (1 ounce) packet taco seasoning
- 1⁄4 cup water
- 1 (10 ounce) can diced tomatoes with green chilies
- 1 green pepper, diced
- 1⁄2 cup onion, diced
- 1 (4 ounce) can diced chilies
- 1⁄2 cup sour cream
- 1⁄2 cup mayonnaise
- 2 cups shredded cheddar cheese, divided
Instructions
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Preheat the oven to 350°F (175°C). Grease a 9×13-inch baking pan with cooking spray.
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Mix the biscuit baking mix and 1 cup of water in a large bowl. Spread the dough evenly in the prepared pan.
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Brown the ground beef in a skillet over medium heat. Add taco seasoning and 1/4 cup water, cooking for 3-5 minutes. Spread over the biscuit layer.
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Top the beef with diced tomatoes and green chilies.
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Sauté green pepper and onion until translucent. Layer over the tomatoes, followed by canned diced chilies.
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Combine sour cream, mayonnaise, and 1 cup of cheese in a bowl. Spread this mixture over the chilies.
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Sprinkle remaining cheese on top.
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Bake for 30-35 minutes until cheese is melted and bubbly. Let cool for 5 minutes before serving.
Possible Substitutes and Variations
- Use ground turkey or chicken instead of beef for a leaner option
- Swap cheddar for pepper jack cheese for extra heat
- Add black beans or corn for additional texture and flavor
- Use low-fat sour cream and mayonnaise for a lighter version
- Incorporate diced jalapeños for those who like it spicier
Serving Suggestions
Serve hot, garnished with fresh cilantro and a dollop of guacamole.
Pair with a crisp green salad to balance the rich flavors.
Offer tortilla chips on the side for scooping up any loose bits.
Accompany with a cold Mexican beer or a tangy margarita for the full Tex-Mex experience.